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The tumor suppressor Brca1 is required for embryonic cellular proliferation in the mouse. Rnf8 deficiency impairs class switch recombination, spermatogenesis, genomic integrity and predisposes for cancer.


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  1. Act normal If you are a high-risk source, avoid saying anything or doing anything after submitting which might promote suspicion.

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  3. Tails If you are at high risk and you have the capacity to do so, you can also access the submission system through a secure operating system called Tails. Please review these basic guidelines.

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